Liver fibrosis from viral hepatitis: advances in non-invasive diagnosis
DOI:
https://doi.org/10.58567/ci02010002Keywords:
Noninvasive; Liver fibrosis; Diagnostic tests; Serum biomarkers; Imaging techniquesAbstract
The stages of liver fibrosis can reflect the severity of chronic viral hepatitis and the probability of liver cancer. Biopsy is still regarded as the reference for staging fibrosis, but the invasive method is not suitable for first-line screening. In recent years, noninvasive methods for detecting virus-driven liver fibrosis have been developed rapidly, which mainly include biological (serum biomarkers indexes) and physical (imaging assessment of liver stiffness) strategies. In this review, we introduce these noninvasive methods, enumerate their diagnosis performances and discuss the role of ferroptosis. At last, we propose directions for future researches.
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